Aktivitas Antibakteri Metabolit Rhizopus sp. Asal Usar Daun Jati terhadap Salmonella typhi
DOI:
https://doi.org/10.21460/sciscitatio.2023.42.130Keywords:
Rhizopus sp., usar daun jati, metabolit, antibakteri, Salmonella typhiAbstract
Kapang Rhizopus sp. berperan sebagai inokulum utama dalam fermentasi tempe. Inokulum dalam fermentasi tempe juga dapat diperoleh secara alami dari usar daun jati. Rhizopus sp. yang tumbuh pada kedelai akan menghasilkan metabolit yang telah dikaji sebagai antidiare yang disebabkan bakteri Salmonella typhi sebagai penyebab demam tifoid yang masih menjadi penyakit endemis di Indonesia. Penelitian ini bertujuan untuk mempelajari aktivitas antibakteri metabolit Rhizopus sp. asal usar daun jati terhadap S. typhi. Metabolit Rhizopus sp. diproduksi pada media Sabouraud Dextrose Broth (SDB) selama 5 hari. Uji antibakteri metabolit mengunakan metode difusi kertas. Isolasi dari usar daun jati memperoleh satu isolat kapang yang teridentifikasi Rhizopus sp. Hasil uji menunjukkan bahwa crude metabolit Rhizopus sp. mempunyai aktivitas antibakteri kategori sedang terhadap S. typhi.
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